Aardvark Therapeutics

Reports to: Chief Medical Officer

Position Summary

The Medical Director (or Senior Medical Director, depending on experience) will lead the medical aspects of assigned clinical trials from concept through completion. This individual will be a key contributor to the planning, execution, and medical oversight of our clinical pipeline, working cross-functionally to ensure the successful delivery of high-quality, compliant clinical studies.

Key Responsibilities

Serve as the medical lead for assigned clinical trials from protocol design through clinical study report. Collaborate with program management, clinical operations, data management, biostatistics, regulatory, and CMC teams to develop and execute trial strategies. Provide medical guidance to investigators and study staff, including protocol training and enrollment support. Author and/or review core clinical documents, including protocols, investigator brochures, informed consent forms, and recruitment materials. Contribute to regulatory documents and interactions, including briefing books, safety updates, submission dossiers, and responses to health authority queries. Oversee or conduct medical monitoring to ensure patient safety and data integrity, including potential direct medical monitor responsibilities for smaller ex-US trials. Analyze and interpret clinical data; prepare reports and presentations for internal and external stakeholders. Participate in the development of Clinical Development Plans (CDPs) and Target Product Profiles (TPPs). Engage with external stakeholders, including KOLs, patient advocacy groups, regulatory agencies, and data monitoring boards. Represent the company at medical and scientific conferences. Maintain up-to-date knowledge of the therapeutic area, competitive landscape, and relevant scientific advances.

Qualifications

MD or DO degree; board certification in Endocrinology preferred. Medical Director: Minimum 4+ years of pharmaceutical or biotech industry experience with leadership of early- and late-stage clinical programs. Senior Medical Director: Minimum of 5+ years of pharmaceutical or biotech industry experience in early- and late-stage clinical programs.  Strong understanding of GCP, clinical trial design, statistical principles, and regulatory/clinical development processes. Excellent leadership, communication, and cross-functional collaboration skills. Exceptional scientific writing and documentation abilities. Ability to thrive in a fast-paced, team-oriented, start-up environment. Strong organizational and problem-solving skills with attention to detail. Willingness to travel up to 20% domestically and internationally.

Salary Range

Base salary of $320,000 – $350,000 per year, depending on experience, qualifications, and role scope.

Pay Transparency Statement:

In accordance with California law (SB 1162), we are providing the expected salary range for this position. The actual compensation offered may vary depending on experience, skills, and location.

We are an Equal Opportunity Employer. All qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or disability status.