No longer accepting applications (expired, filled, etc.)
Mirum Pharmaceuticals, Inc.
Senior Director, Global Medical Affairs Lead - LIV/BAP
The Sr. Director, Global Medical Affairs Lead is responsible for shaping and executing the global medical strategy for assigned therapeutic areas or products. This role provides scientific leadership, evidence generation, external engagement, and cross-functional alignment to support product development, launch, and lifecycle management.
Key Responsibilities
- • Lead the development of the Global Medical Affairs Plan (MAP), including strategic imperatives, medical objectives, tactics, evidence generation priorities, and scientific communication plans in collaboration with members of the Global Medical Affairs Team (GMAT) and aligned with the global brand plan.
- • Provide global medical and scientific leadership for lifecycle management including launch and post-launch activities across regions.
- • Ensure alignment with global brand strategy, clinical development plans, and regional medical needs.
- • Lead, support and manage medical communications and publications including full-time employee(s) managing those initiatives.
- • Collaborate with Scientific Affairs in evidence generation strategies, including real-world evidence (RWE), expanded access programs (EAP), Phase 3b/4 studies, observational research, externally sponsored research (ESR) programs, and HEOR initiatives.
- • Partner with Clinical Development teams to ensure data generation addresses scientific, regulatory, and commercial needs.
- • Oversee publication strategy and execution, ensuring quality, scientific rigor, and compliance with internal and external standards.
- • Serve as the internal subject matter expert for the assigned therapeutic area or product.
- • Interpret emerging scientific and clinical data and communicate implications to internal stakeholders.
- • Maintain deep knowledge of disease state, treatment paradigms, competitive landscape, and clinical guidelines.
- • Lead a key global opinion leader (KOL) engagement strategy and ensure compliant scientific exchange with external experts.
- • Partner with regional and local medical teams to coordinate steering committees, advisory boards, investigator meetings, congress activities, and scientific meetings.
- • Lead medical education initiatives in collaboration with global and regional teams.
- • Represent Medical Affairs in interactions with academic institutions, professional societies, and patient advocacy organizations.
- • Collaborate with Commercial, Clinical Development, Regulatory, Safety, Market Access, and HEOR to support integrated development and commercialization planning.
- • Provide medical input into global brand plans, launch readiness activities, forecasting, and lifecycle management decisions.
- • Support cross-functional teams with scientific insights, training, and medical review of materials.
- • Ensure full compliance with company standard operating procedures (SOPs), regulatory requirements, and applicable laws and industry guidelines.
- • Complete core compliance curriculum in a timely manner, as assigned by executive leadership.
Required
- • Advanced scientific or clinical degree (e.g., MD, DO, Pharm.D., PhD, PA, NP).
- • Significant experience in Medical Affairs, with demonstrated global or regional leadership responsibilities.
- • Minimum of 2 years of management experience is required
- • Experience in generating a scientific communication strategy, including publications, symposia, advisory boards, medical education, etc.
- • Strong ability to understand, synthesize, and communicate complex scientific and clinical information.
- • Demonstrated strategic thinking and leadership capabilities.
- • Excellent oral, written, and presentation skills.
- • Proven ability to work cross-functionally in a matrixed organization.
- • Strong business acumen and understanding of drug development and commercialization.
- • High level of professionalism, integrity, and compliance mindset
- • Adhere and follow Mirum corporate values of “Be Real, Get it Done, Care and Have Fun Seriously.”
Preferred
- • Experience supporting product development and/or launch preferred.
- • Rare disease experience and/or specialty therapeutic area experience preferred.
MISSION
Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we’re looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously.
Position Summary
The Sr. Director, Global Medical Affairs Lead (GMAL) for the ALGS/PFIC and Bile Acid Programs is an internal medical affairs senior strategic leader responsible for shaping and executing the global medical strategy for the assigned therapeutic area or product. This role provides strong scientific leadership, evidence generation, external engagement, and cross-functional alignment to support successful product development, launch, and lifecycle management. The GMAL is the medical affairs strategic lead for an asset(s)collaborating closely with Scientific Affairs, Clinical Development, Marketing, Market access, Safety, and global regional medical teams to ensure alignment with global brand strategy and scientific priorities.
Global Medical Strategy & Leadership
Education / Experience
Mirum Pharmaceuticals provides reasonable accommodation for qualified individuals with disabilities and disabled veterans in job application procedures.
Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we’re looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously.
Position Summary
The Sr. Director, Global Medical Affairs Lead (GMAL) for the ALGS/PFIC and Bile Acid Programs is an internal medical affairs senior strategic leader responsible for shaping and executing the global medical strategy for the assigned therapeutic area or product. This role provides strong scientific leadership, evidence generation, external engagement, and cross-functional alignment to support successful product development, launch, and lifecycle management. The GMAL is the medical affairs strategic lead for an asset(s)collaborating closely with Scientific Affairs, Clinical Development, Marketing, Market access, Safety, and global regional medical teams to ensure alignment with global brand strategy and scientific priorities.
- This role will require both US and international travel at a minimum of 40-50%
Global Medical Strategy & Leadership
- Lead the development of the Global Medical Affairs Plan (MAP), including strategic imperatives, medical objectives, tactics, evidence generation priorities, and scientific communication plans in collaboration with members of the Global Medical Affairs Team (GMAT) and aligned with the global brand plan.
- Provide global medical and scientific leadership for lifecycle management including launch and post-launch activities across regions.
- Ensure alignment with global brand strategy, clinical development plans, and regional medical needs.
- Lead, support and manage medical communications and publications including full-time employee(s) managing those initiatives.
- Collaborate with Scientific Affairs in evidence generation strategies, including real-world evidence (RWE), expanded access programs (EAP), Phase 3b/4 studies, observational research, externally sponsored research (ESR) programs, and HEOR initiatives.
- Partner with Clinical Development teams to ensure data generation addresses scientific, regulatory, and commercial needs.
- Oversee publication strategy and execution, ensuring quality, scientific rigor, and compliance with internal and external standards.
- Serve as the internal subject matter expert for the assigned therapeutic area or product.
- Interpret emerging scientific and clinical data and communicate implications to internal stakeholders.
- Maintain deep knowledge of disease state, treatment paradigms, competitive landscape, and clinical guidelines.
- Lead a key global opinion leader (KOL) engagement strategy and ensure compliant scientific exchange with external experts.
- Partner with regional and local medical teams to coordinate steering committees, advisory boards, investigator meetings, congress activities, and scientific meetings.
- Lead medical education initiatives in collaboration with global and regional teams.
- Represent Medical Affairs in interactions with academic institutions, professional societies, and patient advocacy organizations.
- Collaborate with Commercial, Clinical Development, Regulatory, Safety, Market Access, and HEOR to support integrated development and commercialization planning.
- Provide medical input into global brand plans, launch readiness activities, forecasting, and lifecycle management decisions.
- Support cross-functional teams with scientific insights, training, and medical review of materials.
- Ensure full compliance with company standard operating procedures (SOPs), regulatory requirements, and applicable laws and industry guidelines.
- Complete core compliance curriculum in a timely manner, as assigned by executive leadership
Education / Experience
- Advanced scientific or clinical degree (e.g., MD, DO, Pharm.D., PhD, PA, NP).
- Significant experience in Medical Affairs, with demonstrated global or regional leadership responsibilities.
- Minimum of 2 years of management experience is required
- Experience supporting product development and/or launch preferred.
- Experience in generating a scientific communication strategy, including publications, symposia, advisory boards, medical education, etc.
- Rare disease experience and/or specialty therapeutic area experience preferred.
- Strong ability to understand, synthesize, and communicate complex scientific and clinical information.
- Demonstrated strategic thinking and leadership capabilities.
- Excellent oral, written, and presentation skills.
- Proven ability to work cross-functionally in a matrixed organization.
- Strong business acumen and understanding of drug development and commercialization.
- High level of professionalism, integrity, and compliance mindset
- Adhere and follow Mirum corporate values of “Be Real, Get it Done, Care and Have Fun Seriously.”
Mirum Pharmaceuticals provides reasonable accommodation for qualified individuals with disabilities and disabled veterans in job application procedures.
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