LeonaBio

About LeonaBio:

LeonaBio, Inc., headquartered in the Seattle, Washington area, is a clinical-stage biopharmaceutical company dedicated to the development of novel therapeutics for high unmet medical needs, including amyotrophic lateral sclerosis (ALS) and treatment-resistant metastatic breast cancer, with the goal of improving patients’ lives. Our lead drug candidates, lasofoxifene and ATH-1105, are novel, small molecule therapies with the potential to address devastating diseases where current treatment options are limited or ineffective. With a strong commitment to scientific excellence and patient-centered innovation, we are dedicated to developing meaningful new therapies for those who need them most.

About this role:

The Senior Director, Medical Affairs serves as the strategic scientific leader for the company’s late-stage oncology asset, driving the development and execution of an integrated global medical affairs strategy. This role provides deep therapeutic expertise, shapes evidence generation priorities, and ensures scientific excellence across all medical activities. A core responsibility is leading medical communication strategy and scientific narrative development, ensuring consistent, high‑quality dissemination of data across internal and external audiences. The Senior Director partners closely with Commercial and cross‑functional teams to ensure medical alignment, scientific readiness, and seamless execution of launch plans that support successful product introduction and sustained market impact.

Responsibilities:

• Lead the development and execution of the medical affairs strategy for the company’s late-stage oncology asset.
• Provide therapeutic expertise to guide strategic decisions, evidence generation priorities, and lifecycle planning.
• Serve as a scientific and strategic partner to Commercial, Clinical Development, Regulatory, and other teams.
• Build and maintain strong relationships with Key Opinion Leaders (KOLs), academic investigators, and professional societies
• Lead scientific engagement strategies at major oncology congresses
• Lead creation and review of high‑quality medical content, including:

-Scientific narratives and core slide decks

-Medical information responses and FAQs

-Advisory board materials

-Training content for field medical teams

• Drive publication planning in partnership with internal authors, external experts, and publication agencies.
• Identify emerging trends, competitive intelligence, and unmet needs to inform strategy and evidence generation
• Provide oversight for medical review of promotional and non‑promotional materials.
• Provide scientific review and expertise for independent investigator-sponsored studies
• Ensure all medical affairs activities adhere to regulatory, legal, and compliance standards

Requirements:

• Advanced medical or scientific degree (MD, PharmD, PhD or equivalent).
• 7-10+ years of experience in Medical Affairs within the biopharmaceutical industry, with significant oncology expertise.
• Strong understanding of oncology clinical development, competitive landscape, and evolving standards of care.
• Demonstrated leadership in medical communications, publication strategy, and scientific narrative development
• Experience interacting with global KOLs, academic institutions, and professional societies.
• Solid understanding of Health Economics and Payer environment is preferred.
• Ability to comprehend and combine complex sets of data.

LeonaBio is an equal opportunity employer and does not unlawfully discriminate against employees or applicants for employment on the basis of an individual’s race, color, religion, creed, sex, national origin, age, disability, marital status, veteran status or any other status protected by applicable law. This policy applies to all terms, conditions and privileges of employment, including recruitment, hiring, placement, compensation, promotion, discipline and termination.