Karyopharm Therapeutics Inc.

Director, Global Medical Communications

The Director of Medical Communications will develop and deliver high-quality oncology medical communication training pieces in a cross-functional environment across a variety of tumor types. The role provides strategic leadership for medical communications, scientific content development, and training support for internal stakeholders while working with external vendors, field-based medical affairs, and cross-functional teams.

Key Responsibilities
  • Developing delivering high quality Oncology medical communication training pieces (print/digital) in a cross-functional environment across a variety of tumor types
  • Build awareness of Karyopharm’s clinical programs and scientific leadership in the field of Oncology
  • Support the differentiation of Karyopharm from competitors
  • Lead the generation and/or dissemination of data to education HCP and other relevant audiences
  • Build strong relationships and collaborations with KOLs and/or principle investigators with initiatives that make Karyopharm a leader with science, innovation and patient focused activities
  • Provide strategic leadership to Medical Communications in support of the oncology field including, but not limited to, educational and training materials for relevant diseases and products
  • Create scientific tools and materials in support of the oncology business including, but not limited to educational/training materials, disease state and product slide kits, etc.
  • Develop scientific programs and materials for internal and external stakeholders
  • Manage the work of external medical communication vendors, providing specific guidance on projects, as well as timelines and quality of deliverables and adherence to budget
  • Act as liaison to field-based medical affairs to produce high-quality and useful communication tools, Slide Decks and training programs
  • Lead the development of high-quality and high-impact scientific content in support of medical affairs, clinical development and other internal stakeholders
  • Contribute to the development, review, and/or refinement of clinical content for advisory boards and investigator meetings
  • Orchestrate the development of a strategic scientific communication tools, including study data compendia and treatment guideline plan summaries
  • Ensure awareness of current trends within the industry, identify benchmarks and establish “best practices” within the function
  • Incorporate tools and strategies that ensure cutting-edge innovation in scientific communications, while remaining in compliance to all policies and regulations
  • Evaluate adherence to policies and/or procedures and implement corrective action when needed
  • Conduct business in accordance with Karyopharm Values
  • Provide clinical and/or scientific information, input and interpretation, as needed
  • Serve as a scientific/clinical content reviewer for communication pieces developed and ultimately submitted to the legal, medical regulatory review team
  • Partner with the Brand team to deliver and/or review scientific content for commercial deliverables
  • Create new training materials, and update existing training materials, as needed
  • Partner with MSL Director on MSL training, both for new hires and for ongoing training workstreams
  • Assess competency of MSLs with MSL Director
  • Coordinate live and Web-based training meetings for internal stakeholders
  • Become a content expert that can deliver training presentations/sessions
  • When applicable, coordinate new hire and ongoing training for other GMSA employees, outside of the MSL team
  • Partner with the other team members on deliverables which include congress planning, congress materials, and other GMSA tools and resources
  • Partner with Sales Training on clinical content of sales training materials
  • Help create pre-congress materials (briefing books, content analysis etc.); congress sessions coverage and reporting plan and post-congress executive summary report
  • Lead the execution of these plans through a cross functional team setting
Required
  • An advanced degree in a related scientific or clinical discipline (MD, PharmD, or PhD) with at least 5 years’ relevant experience in the pharmaceutical or biotechnology industry in Medical/Scientific Communications
  • Experience in the development of MSL training materials, disease state awareness, mechanism of action and other educational pieces (digital and print) required
  • Knowledge and understanding of relevant clinical development programs and therapeutic issues
  • Ability to create and present on scientific and clinical data in alignment with Global requirements and “Best Practices”
  • Proficiency in scientific literature searches, analysis, and evaluation
  • Strong human and project leadership and management history required
  • Display working knowledge on legal and regulatory guidelines in the pharmaceutical industry
  • Solid understanding of drug development and life-cycle development/management
  • Excellent communication and diplomacy skills and capability of effectively combining science and relationship building
  • Ability to work effectively with key decision makers, both within and outside the company
  • Ability to make decisions in a timely manner even in the face of incomplete information or tight timelines and pressure
  • Ability to manage multiple projects in a fast-paced environment
  • Exceptional organization and project planning skills
  • Well spoken, confident, enthusiastic and charismatic
  • Must be able to work in cross-functional teams across the organization in a dynamic environment
  • Willingness to travel (up to 20–30%) to represent Karyopharm at medical conferences, presentations, and other meetings
Preferred
  • Oncology training or experience in solid and/or hematologic malignancies preferred
  • Preference will be given to candidates with knowledge in the therapeutic area of interest
  • Prior experience in a commercial organization is a plus
  • Prior experience in the pre-launch planning of oncology products is highly desirable
Benefits & Perks
  • comprehensive benefits (medical, dental, vision, 401(k), and more)
  • equity
  • the potential to receive annual target bonuses
R

Responsibilities

The Director of Medical Communications will be a member of Global Medi cal and Scientific Affairs team. Reporting to the Head of Medical Communications/ P ublications, t he candidate will be responsible for developing delivering high quality Oncology medical communication trainin g pieces (print/digital) in a cross-functional environment across a variety of tumor types . The role supports the following strategic imperatives :

  • B uild awareness of Karyopharm’s clinic al programs and scientific leadership in the field of Oncology
  • Suppor t the differentiation of Karyopharm from competitors
  • Lead the generation and/or dissemination of data to education HCP and other relevant audiences
  • Build strong relationships and collaborations with KOLs and/or principle investigators with initiatives that make Karyopharm a leader with science, innovation and patient focused activities.

Responsibilities

Medical Communications:

  • Pr ovide strategic leadership to Medical Communications in support of the oncology field including, but not limited to , educational and training materials for relevant diseases and products.
  • Create scientific tools and materials in support of the oncology business including, but not limited to educational/training materials, disease state and product slide kits, etc.
  • Develop scientific programs and materials for internal and external stakeholders
  • Manage the work of external medical communication vendors , providing specific guidance on projects, as well as timeline ss and quality of deliverables and adherence to budget.
  • Act as liaison to field-based medical affairs to produce high-quality and usefu l communication tools, Slide Decks and training programs
  • Lead the development of high - quality and high - impact scientific content in support of medical affairs, clinical development and other internal stakeholders .
  • Contribute to the development , review, and/or refinement of clinical content for advisory boards and investigator meetings.
  • Orchestrate the development of a strategic scientific communication tools, including study data compend ia and treatment guideline plan summaries .
  • Ensure awareness of current trends within the industry, identify benchmarks and establish “best practices” within the function.
  • Incorporate tools and strategies that ensure cutting-edge innovatio n in scientific communications, while remaining in compliance to all policies and regulations.
  • Evaluate adherence to policies and/or procedures and implement corrective action when needed.
  • Conduct business in accordance with Karyopharm Values.
  • Provide clinical and/or scientific information, input and interpretation , as needed
  • Serve as a scientific/clinical content reviewer for communication pieces developed and ultimately submitted to the legal, medical regulatory review team
  • Partner with the Brand team to deliver and/or review scientific content for commercial deliverables
  • Create new training materials , and upda te existing training materials, as needed.
  • Partner with MSL Director on MSL training, both for new hire s and for ongoing training workstreams
  • Assess competency of MSLs with MSL Director
  • Coordinate live and Web-based training meetings for internal stakeholders
  • Become a content expert that can deliver training presentations/sessions
  • When applicable, coordinate new hire and ongoing training for other GMSA employees, outside of the MSL team
  • Partner with the other team members on deliverables which include congress planning, congress materials, and other GMSA tools and resources.
  • Partner with Sales Training on clinical content of sales training materials
  • Help c reate pre-congress materials (briefing books, content analysis etc.); congress sessions coverage and reporting plan and post - congress executive summary report.
  • Lead the execution of these plans through a cross functional team setting.

Qualifications

Candidate Profile & Requirements:

  • A n advanced degree in a related scientific or clinical discipline ( MD, PharmD, or PhD) with at least 5 years’ relevant experience in the pharmaceutical or biotechnology industry in Medical /Scientific Communications
  • Oncology training or experience in solid and/or hematologic malignancies preferred.
  • Experience in the development of MSL training materials, disease state awareness, mechanism of action and other educational pieces (digital and print) required
  • Preference will be given to candidates with knowledge in the therapeutic area of interest.
  • Prior experience in a commercial organization is a plus.
  • Prior experience in the pre- launch planning of oncology products is highly desirable
  • Knowledge and understanding of relevant clinical development programs and therapeutic issues.
  • Ability to create and present on scientific and clinical data in alignment with Global requirements and “Best Practices ”.
  • Proficiency in scientific literature searches, analysis, and evaluation.
  • Strong human and project leadership and management history required .
  • Display working knowledge on legal and regulatory guidelines in the pharmaceutical industry.
  • Solid understanding of drug development and life-cycle development/ management.
  • Excellent communication and diplomacy skills and capability of effectively combining science and relationship building.
  • Ability to work effectively with key decision makers, both within and outside the company.
  • Ability to make decisions in a timely manner even in the face of incomplete information or tight timelines and pressure.
  • Ability to manage multiple projects in a fast-paced environment.
  • Exceptional organization and project planning skills.
  • Well spoken, confident, enthusiastic and charismatic
  • Must be able to work in cross-functional teams across the organization in a dynamic environment.
  • Willingness to travel ( up to 20–30%) to represent Karyopharm at medical conferences, presentations, and other meetings.

At Karyopharm, base pay is one part of a competitive total rewards package that includes comprehensive benefits (medical, dental, vision, 401(k), and more), equity and the potential to receive annual target bonuses. Actual pay is based on factors such as location, experience, skills, education, and internal equity. We maintain broad salary ranges to reflect market conditions and the specialized nature of our work. The anticipated base salary range for this position is $210 K - $250 K USD.

Our Value Proposition

This is a uniquely exciting time to join Karyopharm Therapeutics where we are pioneering the science of nuclear export inhibition to develop differentiated therapies for patients with cancer. We are building upon an established commercial foundation in multiple myeloma while advancing the potential of selinexor across additional hematologic and solid tumor cancers including myelofibrosis and TP53 wild-type endometrial cancer, areas where patients continue to face significant unmet needs.

Our lead therapy, XPOVIO ® (selinexor), is a first-in-class inhibitor of exportin 1 (XPO1) and is approved in the U.S. for adults with relapsed or refractory multiple myeloma, with approvals in more than 50 countries and territories outside the U.S. We are also exploring opportunities to evaluate XPO1 inhibition across myeloproliferative neoplasms and TP53 wild-type driven solid tumors using next-generation compounds, including eltanexor.

As we prepare for our next phase of growth, we are continuing to invest in critical capabilities across the organization to support future opportunities and deepen our impact in oncology. We are looking for talented people who are motivated by meaningful work, energized by growth and momentum, and excited by the opportunity to help shape what comes next in a collaborative, fast-moving environment where individual contributions are visible and valued.

Learn more at Karyopharm Therapeutics .
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