Delcath Systems

Job Title:

Senior Director or Director of Medical Research and Strategy- US

Department:

Medical Affairs

Location:

Remote

Reports To:

Vice President, Global Medical Affairs

Date Prepared:

June 2026

POSITION SUMMARY

The Senior Director or Director Medical Research and Strategy (MR&S) for the United States (US) will be part of the Global Delcath Medical Affairs team and lead the development and execution of an integrated scientific and evidence generation plans (EGPs) to address knowledge gaps in the of percutaneous hepatic perfusion (PHP) within metastatic uveal melanoma and expand its clinical application in other solid tumors with hepatic metastases. This role will also play a key role in supporting commercial and field medical affairs to drive strategic engagement, data dissemination and program development across commercial sites within the US and possibly Canada. This role will report to the Vice President of Global Medical Affairs.

ESSENTIAL DUTIES AND RESPONSIBILITIES include the following. Other duties may be assigned.

• Strategic Leadership: Develop and execute comprehensive, multi-year medical affairs strategies for including life cycle management to address knowledge gaps with mUM and disease states beyond the current indication


• Evidence Generation: Collaborate and support the PHP-Working Groups for Europe and collaborative research model involving multi-center and single center Investigator-Initiated Trials (IITs) and real-world evidence (RWE) initiatives to address data gaps for the US


• Field support and competitive intelligence: Coordinate, support, and provide strategic guidance on field engagement, insight gathering, and tracking involving MSL field teams in the US


• Scientific Communication: Collaborate with colleagues within MR&S to support publication strategies and the creation of scientific content (slide decks, medical education materials)


• KOL Engagement: Cultivate relationships with key opinion leaders, healthcare professionals, and cooperative groups to gather insights and drive scientific exchange


• Cross-Functional Collaboration: Align Medical Affairs strategies with Clinical Development, Commercial, and Regulatory teams across to support the US region

SUPERVISORY RESPONSIBILITIES

This position can have up to five direct reports based on qualifications and after appropriate onboarding.

QUALIFICATIONS

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodation may be made to enable individuals with disabilities to perform the essential functions.

EDUCATION and/or EXPERIENCE

• Education: Advanced scientific degree required: MD, PhD, or Pharm D.


• Experience: Substantial experience (typically 5 - 10 years) in medical affairs, oncology clinical research, or a related role within the pharmaceutical industry is preferred


• Expertise: Deep scientific knowledge in solid tumor oncology and experience with clinical trial design, biostatistics, and study execution


• Skills: Strong leadership, communication, strategic thinking, and ability to work in a matrixed environment.

LANGUAGE SKILLS

Ability to read and interpret documents such as technical journals, safety rules, operating and maintenance instructions, and procedure manuals. Ability to write routine reports and correspondence. Ability to speak effectively with employees and outside organizations.

PHYSICAL DEMANDS

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodation may be made to enable individuals with disabilities to perform the essential functions.

While performing the duties of this job, the employee is regularly required to sit, stand or walk and talk or hear. The employee is frequently required to use hands to finger, handle, or feel and reach with hands and arms; and is subject to repetitive motions of the wrists, hands, and/or fingers. The employee must occasionally lift and/or move up to 10 pounds. Specific vision abilities required by this job include close vision, distance vision, peripheral vision, depth perception, and ability to adjust focus.

WORK ENVIRONMENT

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodation may be made to enable individuals with disabilities to perform the essential functions.