Belenos Biosciences Inc.

Medical Director, Clinical Development

Location: Hybrid/Remote

Biologics | Inflammation | Immunology

Belenos Biosciences is a clinical-stage biotech developing innovative biologics for chronic inflammatory diseases, including asthma, COPD, atopic dermatitis, and other immunologic conditions. With multiple bispecific programs advancing into clinical development, we are building a world-class team to bring transformative medicines to patients globally. We value scientific excellence, operational rigor, out-of-the-box thinking and have a culture built on accountability, collaboration, and joy. 

About the Role

The Medical Director will provide medical and scientific support across clinical programs, contributing to clinical strategy, protocol development, and the execution of Phase 1–3 trials. This role works closely with Clinical Operations, Regulatory, Biometrics, Safety, Translational Medicine, and external investigators to ensure high-quality and efficient clinical development. This is a remote role within the United States and reports to the Vice President, Clinical Development.

Responsibilities

• Work collaboratively within a cross-functional clinical development team to support the planning, execution, and interpretation of clinical trials from start-up through completion.
• Contribute to the design, writing, and review of study synopses, protocols, amendments, informed consent forms, and updates to the Investigator’s Brochure to ensure scientific rigor and clear assessment of safety, PK/PD, and efficacy.
• Provide day-to-day medical monitoring for ongoing studies, including eligibility assessments, safety review, dose-escalation support, and review of protocol deviations and compliance.
• Collaborate closely with Pharmacovigilance to evaluate clinical safety data, prepare safety summaries, and support internal safety reviews.
• Collaborate with Clinical Operations to facilitate efficient trial execution and support operational activities relevant to clinical oversight.
• Participate in vendor evaluation and study start-up activities, including development of operational and medical study plans.
• Engage with CRO teams, investigators, and clinical sites to address medical questions, support patient recruitment, and ensure high-quality study conduct.
• Review and interpret clinical data; contribute to SAP development and TLF review
• Support preparation of regulatory submissions, including IND/CTA filings, safety updates, briefing documents, and responses to health authority questions.
• Contribute to clinical study reports and related analyses at study close-out.
• Participate in KOL engagements, advisory boards, and scientific discussions relevant to program strategy and study design.
• Foster a collaborative, accountable, and scientifically rigorous team culture, ensuring compliance with regulations, SOPs, and ethical standards.
• Communicate effectively across functional groups and bring a proactive, hands-on approach to resolving issues and advancing clinical program.

Qualifications

• MD (or equivalent) required
• 3–5+ years of experience in clinical development within biotech, pharma, or CRO
• Background in immunology, respiratory, dermatology, or inflammatory diseases strongly preferred
• Experience designing and executing clinical trials and providing medical oversight
• Strong communication, analytical thinking, and cross-functional leadership skills

CONTACT: Please send cover letter and CV to Daniel Franjic, dfranjic@belenosbio.com