Formation Bio
Senior Director, Medical Affairs
The Senior Director, Medical Affairs is a leadership role responsible for building and leading Medical Affairs capabilities across a growing portfolio, focusing initially on the lead asset, Sprifermin. This role partners strategically with Clinical Development, Regulatory, Commercial, and Portfolio teams to embed Medical Affairs strategy, scientific exchange, and evidence generation early in development and commercialization.
Key Responsibilities
- • Lead medical affairs and scientific strategy across assigned programs, from late development through pre-launch and commercialization readiness.
- • Embed medical perspective early in development planning, including endpoint selection, evidence generation, and lifecycle strategy.
- • Provide medical and scientific input into asset diligence, in-licensing evaluations, and portfolio strategy.
- • Develop and execute a comprehensive KOL engagement strategy, building durable relationships with external experts, investigators, and scientific leaders.
- • Lead scientific exchange activities, including advisory boards, congress strategy, and external data communication.
- • Serve as a credible scientific leader representing Formation Bio programs externally with rigor and integrity.
- • Own publication planning and execution, ensuring timely, compliant dissemination of clinical and real-world data.
- • Support Phase IV, real-world evidence (RWE), and observational studies in partnership with Clinical and internal stakeholders.
- • Translate evidence into clear medical narratives that inform development, access, and launch readiness.
- • Establish scalable medical affairs processes, governance, and operating models appropriate for a multi-asset organization.
- • Build and lead the Medical Affairs function over time, including the planned launch and management of a field-based Medical Science Liaison (MSL) team.
- • Balance internal capabilities with external vendors and partners to maximize efficiency and impact.
- • Support launch readiness through medical education strategy, scientific positioning, and internal training.
- • Provide medical affairs input into value narratives, HEOR strategy, and reimbursement dossiers in collaboration with cross-functional teams.
- • Develop strategy for engagement with patient advocacy groups and medical societies to inform development, education, and access.
Required
- • 10+ years of experience in Medical Affairs and/or Clinical Development within biopharma or biotech, with increasing leadership responsibility.
- • Advanced scientific or clinical degree (PhD, PharmD, MD, or equivalent) strongly preferred.
- • Demonstrated experience developing and executing medical strategy across late development, pre-launch, and commercialization.
- • Experience building or scaling medical affairs capabilities, including MSL teams.
- • Deep understanding of medical compliance, scientific exchange regulations, and industry best practices.
- • Strong cross-functional partner with experience working closely with Clinical, Regulatory, Commercial, and Portfolio teams.
- • Track record of credible external engagement with KOLs, investigators, and scientific stakeholders.
- • Exceptional communication skills with the ability to synthesize complex data into clear strategic insights.
- • Hands-on leadership style with comfort operating in a fast-growing, resource-lean environment.
Benefits & Perks
- • Equity
- • Comprehensive benefits
- • Generous perks
- • Hybrid flexibility
About Formation Bio
Formation Bio is a tech and AI driven pharma company differentiated by radically more efficient drug development.
Advancements in AI and drug discovery are creating more candidate drugs than the industry can progress because of the high cost and time of clinical trials. Recognizing that this development bottleneck may ultimately limit the number of new medicines that can reach patients, Formation Bio, founded in 2016 as TrialSpark Inc., has built technology platforms, processes, and capabilities to accelerate all aspects of drug development and clinical trials. Formation Bio partners, acquires, or in-licenses drugs from pharma companies, research organizations, and biotechs to develop programs past clinical proof of concept and beyond, ultimately helping to bring new medicines to patients. The company is backed by investors across pharma and tech, including a16z, Sequoia, Sanofi, Thrive Capital, Sam Altman, John Doerr, Spark Capital, SV Angel Growth, and others.
You Can Read More At The Following Links
About The Position
The Senior Director, Medical Affairs is a first-in-function leadership role responsible for building and leading Medical Affairs capabilities across Formation Bio’s growing portfolio. This role will establish the scientific foundation for programs spanning late-stage development to commercialization, with an initial focus on our lead asset, Sprifermin.
This leader will serve as a strategic scientific partner to Clinical Development, Regulatory, Commercial, and Portfolio teams, ensuring that Medical Affairs strategy, scientific exchange, and evidence generation are embedded early and executed with rigor, compliance, and credibility.
The Senior Director will design scalable medical affairs infrastructure, lead external scientific engagement, and build a high-impact Medical Affairs team—including the future build-out of a field-based Medical Science Liaison (MSL) team.
Responsibilities
Medical & Scientific Strategy
Compensation
The target salary range for this role is: $325,000 - $425,000
Salary ranges are informed by a number of factors including geographic location. The range provided includes base salary only. In addition to base salary, we offer equity, comprehensive benefits, generous perks, hybrid flexibility, and more. If this range doesn't match your expectations, please still apply because we may have something else for you.
You will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.
Formation Bio is a tech and AI driven pharma company differentiated by radically more efficient drug development.
Advancements in AI and drug discovery are creating more candidate drugs than the industry can progress because of the high cost and time of clinical trials. Recognizing that this development bottleneck may ultimately limit the number of new medicines that can reach patients, Formation Bio, founded in 2016 as TrialSpark Inc., has built technology platforms, processes, and capabilities to accelerate all aspects of drug development and clinical trials. Formation Bio partners, acquires, or in-licenses drugs from pharma companies, research organizations, and biotechs to develop programs past clinical proof of concept and beyond, ultimately helping to bring new medicines to patients. The company is backed by investors across pharma and tech, including a16z, Sequoia, Sanofi, Thrive Capital, Sam Altman, John Doerr, Spark Capital, SV Angel Growth, and others.
You Can Read More At The Following Links
- Our Vision for AI in Pharma
- Our Current Drug Portfolio
- Our Technology & Platform
About The Position
The Senior Director, Medical Affairs is a first-in-function leadership role responsible for building and leading Medical Affairs capabilities across Formation Bio’s growing portfolio. This role will establish the scientific foundation for programs spanning late-stage development to commercialization, with an initial focus on our lead asset, Sprifermin.
This leader will serve as a strategic scientific partner to Clinical Development, Regulatory, Commercial, and Portfolio teams, ensuring that Medical Affairs strategy, scientific exchange, and evidence generation are embedded early and executed with rigor, compliance, and credibility.
The Senior Director will design scalable medical affairs infrastructure, lead external scientific engagement, and build a high-impact Medical Affairs team—including the future build-out of a field-based Medical Science Liaison (MSL) team.
Responsibilities
Medical & Scientific Strategy
-
- Lead medical affairs and scientific strategy across assigned programs, from late development through pre-launch and commercialization readiness.
- Embed medical perspective early in development planning, including endpoint selection, evidence generation, and lifecycle strategy.
- Provide medical and scientific input into asset diligence, in-licensing evaluations, and portfolio strategy.
-
- Develop and execute a comprehensive KOL engagement strategy, building durable relationships with external experts, investigators, and scientific leaders.
- Lead scientific exchange activities, including advisory boards, congress strategy, and external data communication.
- Serve as a credible scientific leader representing Formation Bio programs externally with rigor and integrity.
-
- Own publication planning and execution, ensuring timely, compliant dissemination of clinical and real-world data.
- Support Phase IV, real-world evidence (RWE), and observational studies in partnership with Clinical and internal stakeholders.
- Translate evidence into clear medical narratives that inform development, access, and launch readiness.
-
- Establish scalable medical affairs processes, governance, and operating models appropriate for a multi-asset organization.
- Build and lead the Medical Affairs function over time, including the planned launch and management of a field-based Medical Science Liaison (MSL) team.
- Balance internal capabilities with external vendors and partners to maximize efficiency and impact.
-
- Support launch readiness through medical education strategy, scientific positioning, and internal training.
- Provide medical affairs input into value narratives, HEOR strategy, and reimbursement dossiers in collaboration with cross-functional teams.
-
- Develop strategy for engagement with patient advocacy groups and medical societies to inform development, education, and access.
- Develop strategy for engagement with patient advocacy groups and medical societies to inform development, education, and access.
- 10+ years of experience in Medical Affairs and/or Clinical Development within biopharma or biotech, with increasing leadership responsibility.
- Advanced scientific or clinical degree (PhD, PharmD, MD, or equivalent) strongly preferred.
- Demonstrated experience developing and executing medical strategy across late development, pre-launch, and commercialization.
- Experience building or scaling medical affairs capabilities, including MSL teams.
- Deep understanding of medical compliance, scientific exchange regulations, and industry best practices.
- Strong cross-functional partner with experience working closely with Clinical, Regulatory, Commercial, and Portfolio teams.
- Track record of credible external engagement with KOLs, investigators, and scientific stakeholders.
- Exceptional communication skills with the ability to synthesize complex data into clear strategic insights.
- Hands-on leadership style with comfort operating in a fast-growing, resource-lean environment.
Compensation
The target salary range for this role is: $325,000 - $425,000
Salary ranges are informed by a number of factors including geographic location. The range provided includes base salary only. In addition to base salary, we offer equity, comprehensive benefits, generous perks, hybrid flexibility, and more. If this range doesn't match your expectations, please still apply because we may have something else for you.
You will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.
Keep track of your job search
Save personal notes for each job to track your thoughts, application status, and follow-ups.
Try for freeUpload your resume
Sign up to upload your resume and get AI-powered customization for job applications.
Sign up freePractice your interview
Get AI-powered mock interviews tailored to this Senior Director, Medical Affairs role. Upload your resume and practice with real-time voice feedback.
Sign up to practice