Eli Lilly and Company
Lead the Real-World Evidence (RWE) function for Lilly Cardiometabolic Health, shaping RWE strategy and managing a team of scientists. Oversee the design and delivery of RWE studies to support registration plans, new uses, and demonstrate the value of medicines across obesity, diabetes, cardiovascular disease, and related metabolic conditions.
Key Responsibilities
- • Provide strategic oversight of the cardiometabolic RWE portfolio, aligning evidence generation with business objectives
- • Work collaboratively with cross-functional partners including Medical Affairs, Commercial, Patient/Regulatory Affairs (PRA), and Development teams to identify evidence gaps and establish project priorities
- • Oversee the design, execution, and delivery of a diverse portfolio of RWE studies across cardiovascular disease, diabetes, obesity, and metabolic disorders
- • Ensure all RWE projects are delivered on time, within budget, and to the highest scientific standards
- • Execute publication and communication strategies that maximize scientific impact and visibility of RWE findings
- • Recruit, develop, and manage a high-performing team of RWE scientists with diverse expertise in epidemiology, biostatistics, health economics, and outcomes research
- • Foster a culture of scientific excellence, innovation, and collaboration within the RWE team
- • Provide mentorship and career development opportunities for team members
- • Build team capabilities in emerging RWE methodologies and data sources
- • Forge strategic partnerships with leading academic institutions, research organizations, and healthcare data companies to access novel data sets and advanced analytic capabilities
- • Identify and evaluate external collaborators with unique data assets (e.g., EHR systems, claims databases, registries, wearable device data)
- • Negotiate and manage collaboration agreements that advance Lilly's RWE objectives
- • Represent Lilly in external scientific forums and maintain relationships with key opinion leaders in real-world evidence
- • Generate real-world evidence to support regulatory submissions and post-approval requirements, working closely with development teams
- • Identify new therapeutic uses and potential New Indication for a Licensed Product (NILEX) opportunities through analysis of real-world data patterns
- • Demonstrate the clinical and economic value of Lilly's cardiometabolic medicines through rigorous comparative effectiveness research, health outcomes studies, and health economic analyses
- • Translate RWE findings into actionable insights for commercial strategy and medical affairs initiatives
- • Ensure all RWE studies adhere to best practices in study design, analysis, and reporting (ISPOR guidelines, STROBE, etc.)
- • Develop and implement innovative methodologies for causal inference, comparative effectiveness, and patient outcomes assessment
- • Drive scientific disclosure through high-impact publications, presentations at major conferences, and engagement with the scientific community
- • Stay current with evolving regulatory guidance on RWE and ensure compliance across all studies
Required
- • PhD, PharmD, MD, or equivalent advanced degree in epidemiology, health services research, outcomes research, biostatistics, or related field
- • Minimum 10 years of experience in real-world evidence, outcomes research, or epidemiology within the pharmaceutical or biotech industry
Preferred
- • Proven track record of leading RWE teams and delivering high-quality evidence generation programs
- • Deep expertise in real-world data sources (claims, EHR, registries) and advanced analytic methods for observational studies
- • Strong understanding of cardiometabolic diseases and their treatment landscape
- • Demonstrated success in establishing and managing external research partnerships
- • Experience supporting regulatory submissions with RWE (FDA, EMA)
- • Excellent scientific writing and communication skills with multiple peer-reviewed publications
- • Strong leadership, collaboration, and influence skills across matrixed organizations
- • Experience with novel data sources including wearables, patient-generated data, and digital health platforms
- • Knowledge of health economics and value demonstration methodologies (HEOR, budget impact, cost-effectiveness)
- • Familiarity with FDA guidance on RWE for regulatory decision-making
- • Experience in cardiometabolic therapeutic categories including incretins, amylins, insulins, and lipid-lowering medications
- • Track record of identifying and advancing NILEX opportunities through RWE
Benefits & Perks
- • Eligibility to participate in a company-sponsored 401(k)
- • Pension
- • Vacation benefits
- • Eligibility for medical, dental, vision and prescription drug benefits
- • Flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
- • Life insurance and death benefits
- • Certain time off and leave of absence benefits
- • Well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)
Company Overview
Industry: Healthcare Technology
Company Size: 500-1,000 employees
Founded: 2015
Headquarters: San Francisco, CA
Company Links
Key Contacts
Contact information not available
About the Company
Leading healthcare technology company focused on improving patient outcomes through innovative digital solutions. We're transforming the way healthcare is delivered with cutting-edge technology and data-driven insights. Our platform serves over 10,000 healthcare professionals and has processed millions of patient interactions.
Recent News & Updates
Position Overview
We are seeking an exceptional leader to lead our Real-World Evidence (RWE) function for Lilly Cardiometabolic Health (CMH). This individual will report to the President of Lilly CMH and sit on the CMH Leadership Team, with responsibility for shaping our RWE strategy and portfolio of projects, managing a team of RWE scientists, delivering strong evidence to support registration plans, new uses and NILEX, and demonstrate the value of our medicines. This includes our portfolio of groundbreaking therapies across obesity, diabetes, cardiovascular disease, and related metabolic conditions.
Key Responsibilities
Strategic Leadership & Portfolio Management
- Provide strategic oversight of the cardiometabolic RWE portfolio, aligning evidence generation with business objectives
- Work collaboratively with cross-functional partners including Medical Affairs, Commercial, Patient/Regulatory Affairs (PRA), and Development teams to identify evidence gaps and establish project priorities
- Oversee the design, execution, and delivery of a diverse portfolio of RWE studies across cardiovascular disease, diabetes, obesity, and metabolic disorders
- Ensure all RWE projects are delivered on time, within budget, and to the highest scientific standards
- Execute publication and communication strategies that maximize scientific impact and visibility of RWE findings
- Recruit, develop, and manage a high-performing team of RWE scientists with diverse expertise in epidemiology, biostatistics, health economics, and outcomes research
- Foster a culture of scientific excellence, innovation, and collaboration within the RWE team
- Provide mentorship and career development opportunities for team members
- Build team capabilities in emerging RWE methodologies and data sources
- Forge strategic partnerships with leading academic institutions, research organizations, and healthcare data companies to access novel data sets and advanced analytic capabilities
- Identify and evaluate external collaborators with unique data assets (e.g., EHR systems, claims databases, registries, wearable device data)
- Negotiate and manage collaboration agreements that advance Lilly's RWE objectives
- Represent Lilly in external scientific forums and maintain relationships with key opinion leaders in real-world evidence
- Generate real-world evidence to support regulatory submissions and post-approval requirements, working closely with development teams
- Identify new therapeutic uses and potential New Indication for a Licensed Product (NILEX) opportunities through analysis of real-world data patterns
- Demonstrate the clinical and economic value of Lilly's cardiometabolic medicines through rigorous comparative effectiveness research, health outcomes studies, and health economic analyses
- Translate RWE findings into actionable insights for commercial strategy and medical affairs initiatives
- Ensure all RWE studies adhere to best practices in study design, analysis, and reporting (ISPOR guidelines, STROBE, etc.)
- Develop and implement innovative methodologies for causal inference, comparative effectiveness, and patient outcomes assessment
- Drive scientific disclosure through high-impact publications, presentations at major conferences, and engagement with the scientific community
- Stay current with evolving regulatory guidance on RWE and ensure compliance across all studies
- PhD, PharmD, MD, or equivalent advanced degree in epidemiology, health services research, outcomes research, biostatistics, or related field
- Minimum 10 years of experience in real-world evidence, outcomes research, or epidemiology within the pharmaceutical or biotech industry
- Proven track record of leading RWE teams and delivering high-quality evidence generation programs
- Deep expertise in real-world data sources (claims, EHR, registries) and advanced analytic methods for observational studies
- Strong understanding of cardiometabolic diseases and their treatment landscape
- Demonstrated success in establishing and managing external research partnerships
- Experience supporting regulatory submissions with RWE (FDA, EMA)
- Excellent scientific writing and communication skills with multiple peer-reviewed publications
- Strong leadership, collaboration, and influence skills across matrixed organizations
- Experience with novel data sources including wearables, patient-generated data, and digital health platforms
- Knowledge of health economics and value demonstration methodologies (HEOR, budget impact, cost-effectiveness)
- Familiarity with FDA guidance on RWE for regulatory decision-making
- Experience in cardiometabolic therapeutic categories including incretins, amylins, insulins, and lipid-lowering medications
- Track record of identifying and advancing NILEX opportunities through RWE
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is
$243,000 - $356,400
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
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