AstraZeneca
US Medical Affairs- Medical Lead
The Medical Lead in US Medical Affairs provides medical leadership for Prostate Cancer/DNA Damage Response (DDR) and leads the Core Medical Team. This role involves developing and executing integrated medical plans, collaborating with internal and external stakeholders, and ensuring alignment of medical strategies with commercial and scientific goals.
Key Responsibilities
- • Lead Medical Affairs activities in Prostate Cancer/DNA Damage Response (DDR) and provide medical leadership to the Core Medical Team (CMT).
- • Lead the development of the integrated medical plans for Lynparza/Saruparib that include tactics to support key strategic imperatives for the disease area/brand.
- • Accountable for the alignment and execution of all activities of the integrated Medical affairs plan, launch plans and budgets.
- • Collaborate with relevant business partners to ensure alignment of medically appropriate brand strategy, planning and execution.
- • Accountable for the medical accuracy and fair balance of medical information in promotional material and learning materials for both internal and external use.
- • Collaborate with global to ensure that the Medical Evidence generation strategy are aligned with business and Medical Affairs’ objectives.
- • Interact with leaders of groups identified as strategic partners, including advocacy, payer and provider groups.
- • Interact with leaders in the therapy area (external experts, Academic Institutions, and Professional Societies).
- • Play an integral role in the planning and participation of national and regional medical advisory boards and speaker training.
- • Collaborate with global to ensure that the medical Externally Sponsored Scientific Research program is aligned with strategy and executed appropriately in the US.
- • Provide medical input into safety profile of the product in collaboration with Patient Safety (PS) physicians.
- • Collaborate with the Medical Science Liaisons and work closely with National Clinical Account Managers to appropriately support key accounts.
- • Provide medical leadership on the design and execution of HEOR studies, outcomes surveys, etc. in close collaboration with Clinical Value Team (CVT).
- • Work closely with the Global Medical Affairs Leader (GMAL) to ensure alignment of US and Global strategies.
Required
- • A Doctor degree in Medicine (M.D, D.O), PhD or PharmD degrees or equivalent will be considered with relevant experience.
- • Experience in other relevant disease areas of interest through clinical experience, biopharmaceutical experience or education may be considered.
- • At least 5+ years of related work experience in industry, clinical or research institution, preferably in oncology, rare disease, or related experiences.
- • Experience in supporting brands or disease area levels in country, regional or global organizations is preferred.
- • Excellent written and oral communication, interpersonal, and organization skills.
- • Strong business acumen, including working knowledge of changing U.S. payer and provider landscape.
- • Proven ability to interact productively with both commercial and scientific / medical colleagues.
- • Demonstrated ability to work collaboratively in cross functional teams.
- • Ability to travel nationally and internationally. Travel will be up to ~30% of time.
Preferred
- • 5+ years of Pharmaceutical Industry experience.
- • Experience in medical affairs particularly oncology/rare disease.
- • Knowledge of relevant Professional Societies and Scientific Medical Experts.
- • Experience with pharmaceutical drug development and Medical/Scientific Affairs.
Benefits & Perks
- • Short-term incentive bonus opportunity.
- • Eligibility to participate in equity-based long-term incentive program (salaried roles).
- • Retirement contribution (hourly roles).
- • Commission payment eligibility (sales roles).
- • Qualified retirement program [401(k) plan].
- • Paid vacation and holidays.
- • Paid leaves.
- • Health benefits including medical, prescription drug, dental, and vision coverage.
Company Overview
Industry: Healthcare Technology
Company Size: 500-1,000 employees
Founded: 2015
Headquarters: San Francisco, CA
Company Links
Key Contacts
Contact information not available
About the Company
Leading healthcare technology company focused on improving patient outcomes through innovative digital solutions. We're transforming the way healthcare is delivered with cutting-edge technology and data-driven insights. Our platform serves over 10,000 healthcare professionals and has processed millions of patient interactions.
Recent News & Updates
Series B
Raised $50M Series B funding - Jan 2024
Award
Named "Best Healthcare Startup" by TechCrunch - Dec 2023
Growth
Expanded to 5 new states - Nov 2023
The Medical Lead in US Medical Affairs is a MD/PhD/PharmD who has a history of clinical or pharmaceutical industry experience in the Oncology/rare disease therapeutic area. The ideal candidate should have significant experience in Oncology and would thrive on proactively engaging internal and external leaders and will serve as a medical expert for their compound(s) and disease area. They will also have strong commercial aptitude and/or experience in product launch, including proven ability to translate and appropriately align commercial and scientific goals and objectives.
The incumbent will develop peer relationships with external scientific experts in Oncology/rare disease therapeutic area. The incumbent is responsible for the development, alignment and execution of the organization's strategy and objectives across Medical Affairs’ functional areas while working closely with internal stakeholders.
This Individual is also accountable for leading and managing Medical Affairs resources and budget in collaboration with commercial and global functional teams.
Major Accountabilities/Responsibilities
Date Posted
03-Feb-2026
Closing Date
30-Mar-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
The incumbent will develop peer relationships with external scientific experts in Oncology/rare disease therapeutic area. The incumbent is responsible for the development, alignment and execution of the organization's strategy and objectives across Medical Affairs’ functional areas while working closely with internal stakeholders.
This Individual is also accountable for leading and managing Medical Affairs resources and budget in collaboration with commercial and global functional teams.
Major Accountabilities/Responsibilities
- The Medical Lead is responsible to lead Medical Affairs activities in Prostate Cancer/DNA Damage Response (DDR) and provides medical leadership to the Core Medical Team (CMT).
- Lead the development of the integrated medical plans for Lynparza/Saruparib that include tactics to support key strategic imperatives for the disease area/brand.
- Accountable for the alignment and execution of all activities of the integrated Medical affairs plan, launch plans and budgets
- Collaborate with relevant business partners to ensure alignment of medically appropriate brand strategy, planning and execution
- Accountable for the medical accuracy and fair balance of medical information in promotional material and learning materials for both internal and external use
- Collaborate with global to ensure that the Medical Evidence generation strategy are aligned with business and Medical Affairs’ objectives.
- Interact with leaders of groups identified as strategic partners, including advocacy, payer and provider groups.
- Interact with leaders in the therapy area (external experts, Academic Institutions, and Professional Societies).
- Play an integral role in the planning and participation of national and regional medical advisory boards and speaker training
- Collaborate with global to ensure that the medical Externally Sponsored Scientific Research program is aligned with strategy and executed appropriately in the US.
- Provide medical input into safety profile of the product in collaboration with Patient Safety (PS) physicians
- Collaborate with the Medical Science Liaisons and work closely with National Clinical Account Managers to appropriately support key accounts.
- Provide medical leadership on the design and execution of HEOR studies, outcomes surveys, etc. in close collaboration with Clinical Value Team (CVT)
- Work closely with the Global Medical Affairs Leader (GMAL) to ensure alignment of US and Global strategies
- A Doctor degree in Medicine (M.D, D.O), PhD or PharmD degrees or equivalent will be considered with relevant experience.
- Experience in other relevant disease areas of interest through clinical experience, biopharmaceutical experience or education may be considered
- At least 5+ years of related work experience in industry, clinical or research institution, preferably in oncology, rare disease, or related experiences
- Experience in supporting brands or disease area levels in country, regional or global organizations is preferred
- Excellent written and oral communication, interpersonal, and organization skills.
- Strong business acumen, including working knowledge of changing U.S. payer and provider landscape.
- Proven ability to interact productively with both commercial and scientific / medical colleagues.
- Demonstrated ability to work collaboratively in cross functional teams.
- Ability to travel nationally and internationally. Travel will be up to ~30% of time.
- 5+ years of Pharmaceutical Industry experience
- Experience in medical affairs particularly oncology/rare disease
- Knowledge of relevant Professional Societies and Scientific Medical Experts.
- Experience with pharmaceutical drug development and Medical/Scientific Affairs
Date Posted
03-Feb-2026
Closing Date
30-Mar-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
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