The Project Scientist will support NIH-funded molecular, computational, and translational research focused on delirium and neuroinflammation. The role involves advanced expertise in epigenetic analysis, bioinformatics, and multimodal data integration to bridge human biospecimens, neuroimaging, and clinical research.
Key Responsibilities
- • Perform advanced molecular analyses of human biospecimens, including DNA methylation and other epigenetic datasets.
- • Conduct bioinformatic and statistical analyses to identify molecular signatures associated with delirium and related neuropsychiatric conditions.
- • Lead the planning, standardization, and quality management of handling and processing human biospecimens (including blood and peripheral tissues), with demonstrated wet-lab expertise required to ensure sample integrity and data quality for genome-wide assays.
- • Develop, implement, and maintain laboratory protocols for biospecimen processing and molecular data management.
- • Contribute to multimodal analyses and integration of clinical data with molecular datasets (including DNA methylation as well as other omics such as RNA-seq and proteomics) and neuroimaging data (MRI); prior experience with these data types is desirable.
- • Collaborate with research team members to support data interpretation, figure generation, and preparation of scientific manuscripts and grant reports.
- • Assist in developing and maintaining reproducible analytical workflows (preprocessing, QC, statistical analysis, and pipeline implementation) for large-scale, multi-platform omics, imaging, and clinical datasets.
- • Mentor trainees and junior researchers in molecular laboratory techniques, bioinformatics, and computational data analysis.
- • Support collaborative research projects and participate in interdisciplinary research meetings and team-based initiatives.
Required
- • M.D., Ph.D. or equivalent in molecular biology, computational biology, neuroscience, bioinformatics, biomedical science, or a related field.
Preferred
- • Prior experience with multimodal data types including DNA methylation, RNA-seq, proteomics, and neuroimaging data (MRI).
Salary range: The salary range for this position is $76,700-$201,900. Total Negotiated Salary (TNS) calculation depending on specialty can range from $76,700-$201,900. The posted UC Salary Scale set the minimum pay determined by rank and/or step at appointment.
Application Window
Open date: April 27, 2026
Next review date: Tuesday, May 12, 2026 at 11:59pm (Pacific Time)
Apply by this date to ensure full consideration by the committee.
Final date: Tuesday, Apr 27, 2027 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.
Position Description
The University of California, Irvine (UCI), Division of Geriatric Medicine and Gerontology, Department of Family Medicine, seeks a Project Scientist at the Assistant, Associate, or Full rank to support NIH-funded molecular, computational, and translational research focused on delirium and neuroinflammation. The Project Scientist will provide advanced expertise in epigenetic analysis, bioinformatics, and multimodal data integration to support studies bridging human biospecimens, neuroimaging, and clinical research.
Responsibilities
Molecular and Computational Research
- Perform advanced molecular analyses of human biospecimens, including DNA methylation and other epigenetic datasets.
- Conduct bioinformatic and statistical analyses to identify molecular signatures associated with delirium and related neuropsychiatric conditions.
- Lead the planning, standardization, and quality management of handling and processing human biospecimens (including blood and peripheral tissues), with demonstrated wet-lab expertise required to ensure sample integrity and data quality for genome-wide assays.
- Develop, implement, and maintain laboratory protocols for biospecimen processing and molecular data management.
- Contribute to multimodal analyses and integration of clinical data with molecular datasets (including DNA methylation as well as other omics such as RNA-seq and proteomics) and neuroimaging data (MRI); prior experience with these data types is desirable.
- Collaborate with research team members to support data interpretation, figure generation, and preparation of scientific manuscripts and grant reports.
- Assist in developing and maintaining reproducible analytical workflows (preprocessing, QC, statistical analysis, and pipeline implementation) for large-scale, multi-platform omics, imaging, and clinical datasets.
- Mentor trainees and junior researchers in molecular laboratory techniques, bioinformatics, and computational data analysis.
- Support collaborative research projects and participate in interdisciplinary research meetings and team-based initiatives.
Basic qualifications (required at time of application)
M.D., Ph.D. or equivalent in molecular biology, computational biology, neuroscience, bioinformatics, biomedical science, or a related field.
Application Requirements
Document requirements
- Curriculum Vitae - Your most recently updated C.V.
- Cover Letter (Optional)
- Statement of Research (Optional)
- Reflective Teaching and Mentoring Statement - See our guidance for writing a reflective teaching statement . (Optional)
- 3 required (contact information only)
About UC Irvine
The University of California, Irvine is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC anti-discrimination policy .
As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.
- “Misconduct” means any violation of the policies or laws governing conduct at the applicant’s previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment or discrimination, as defined by the employer.
- UC Sexual Violence and Sexual Harassment Policy
- UC Anti-Discrimination Policy for Employees, Students and Third Parties
- APM - 035: Affirmative Action and Nondiscrimination in Employment .
Job location
Orange, CA
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