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What is Clinical Research Operations?
Clinical research operations involves conducting clinical trials at research sites. Physicians serve as Principal Investigators (PIs) or Sub-Investigators (Sub-Is), directly overseeing patient enrollment and study procedures.
Key Responsibilities
- Serve as Principal Investigator for clinical trials
- Oversee patient screening, enrollment, and study visits
- Ensure protocol compliance and patient safety
- Manage relationships with sponsors and CROs
- Lead research site staff (coordinators, nurses)
- Report adverse events and manage safety
Common Job Titles
- Principal Investigator
- Sub-Investigator
- Medical Director, Clinical Research
- Research Physician
- Site Medical Director
Skills and Qualifications
Required:
- MD with active medical license
- GCP (Good Clinical Practice) certification
- Ability to enroll and manage patients
- Strong documentation skills
Preferred:
- Prior clinical trial experience
- Board certification
- Established patient population
- Research site management experience
Compensation Range
- Part-time PI work: $100 - $300 per patient visit
- Full-time research physician: $200,000 - $350,000
- Medical Director: $250,000 - $400,000